The depression of spinal inhibition by morphine

@article{Curtis2005TheDO,
  title={The depression of spinal inhibition by morphine},
  author={D. R. Curtis and A. Duggan},
  journal={Agents and Actions},
  year={2005},
  volume={1},
  pages={14-19}
}
Electrophoretically administered morphine and codeine, but not meperidine, blocked the inhibitory effect of glycine on spinal neurones, without reducing the effectiveness of GABA. This action of morphine was similar to, but much weaker than, that of strychnine.When administered intravenously in divided doses to circumvent marked circulatory disturbances, morphine reduced the direct and recurrent inhibition of spinal motoneurones in a parallel fashion. Again morphine was a very weak strychnine… Expand
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