The dependence of motoneurone membrane potential on extracellular ion concentrations studied in isolated rat spinal cord.

@article{Forsythe1988TheDO,
  title={The dependence of motoneurone membrane potential on extracellular ion concentrations studied in isolated rat spinal cord.},
  author={Ian D. Forsythe and Stephen J. Redman},
  journal={The Journal of physiology},
  year={1988},
  volume={404},
  pages={83-99}
}
1. Intracellular recordings from ninety-nine motoneurones have been made in an in vitro hemisected spinal cord preparation. Their mean resting membrane potential in normal artificial cerebrospinal fluid (CSF) was -71 +/- 0.5 mV (+/- S.E.M.). The mean amplitude of the action potential was 84.0 +/- 1.4 mV (n = 50), and the mean input conductance was 101 +/- 7 nS (n = 49). 2. Both membrane potential and input conductance were sensitive to changes in [K+]o, [Na+]o, [Cl-]o and [Ca2+]o. 3… CONTINUE READING