The dependence of lipid asymmetry upon polar headgroup structure.

  title={The dependence of lipid asymmetry upon polar headgroup structure.},
  author={Mijin Son and Erwin London},
  journal={Journal of lipid research},
  volume={54 12},
The effect of lipid headgroup structure upon the stability of lipid asymmetry was investigated. Using methyl-β-cyclodextrin -induced lipid exchange, sphingomyelin (SM) was introduced into the outer leaflets of lipid vesicles composed of phosphatidylglycerol, phosphatidylserine (PS), phosphatidylinositol, or cardiolipin, in mixtures of all of these lipids with phosphatidylethanolamine (PE), and in a phosphatidylcholine/phosphatidic acid mixture. Efficient SM exchange (>85% of that expected for… CONTINUE READING
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