The dendritic cell receptor DC-SIGN discriminates among species and life cycle forms of Leishmania.

@article{Colmenares2004TheDC,
  title={The dendritic cell receptor DC-SIGN discriminates among species and life cycle forms of Leishmania.},
  author={Mar{\'i}a Colmenares and {\'A}ngel L Corb{\'i} and Salvatore Joseph Turco and Luis Enrique Urbina Rivas},
  journal={Journal of immunology},
  year={2004},
  volume={172 2},
  pages={1186-90}
}
Infection of dendritic cells by the human protozoal parasite Leishmania is part of its survival strategy. The dendritic cell receptors for Leishmania have not been established and might differ in their interactions among Leishmania species and infective stages. We present evidence that the surface C-type lectin DC-SIGN (CD 209) is a receptor for promastigote and amastigote infective stages from both visceral (Leishmania infantum) and New World cutaneous (Leishmania pifanoi) Leishmania species… CONTINUE READING

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