The deleterious or beneficial effects of different agents in intracerebral hemorrhage: think big, think small, or is hematoma size important?

@article{Keep2005TheDO,
  title={The deleterious or beneficial effects of different agents in intracerebral hemorrhage: think big, think small, or is hematoma size important?},
  author={Richard F. Keep and Guohua Xi and Y -J. Hua and Julian T. Hoff},
  journal={Stroke},
  year={2005},
  volume={36 7},
  pages={1594-6}
}
BACKGROUND AND PURPOSE Thrombin, heme oxygenase, complement, microglia activation, and leukocyte infiltration are all actively upregulated in intracerebral hemorrhage (ICH). Experimental evidence suggests that all these factors are involved in ICH-induced brain injury. This suggests a scenario whereby ICH actively (through gene and protein upregulation) induces pathways that result in brain injury. SUMMARY OF REVIEW In this comment, we suggest a potential answer to this conundrum. The… CONTINUE READING

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. Thrombin , heme oxygenase , complement , microglia activation , and leukocyte infiltration are all actively upregulated in intracerebral hemorrhage ( ICH ) .
. Thrombin , heme oxygenase , complement , microglia activation , and leukocyte infiltration are all actively upregulated in intracerebral hemorrhage ( ICH ) .
The deleterious or beneficial effects of different agents in intracerebral hemorrhage : think big , think small , or is hematoma size important ? .
The deleterious or beneficial effects of different agents in intracerebral hemorrhage : think big , think small , or is hematoma size important ? .
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