The delayed type hypersensitivity assay using protein and xenogeneic cell antigens.

@article{Dietert2010TheDT,
  title={The delayed type hypersensitivity assay using protein and xenogeneic cell antigens.},
  author={Rodney Dietert and Terry Lee Bunn and Ji-Eun Lee},
  journal={Methods in molecular biology},
  year={2010},
  volume={598},
  pages={185-94}
}
The delayed-type hypersensitivity (DTH) assay has a lengthy history in immunotoxicity testing since it was one of the original functional assays included in the National Toxicology Program (NTP) immunotoxicology test panel. Based on NTP data analysis, the DTH assay is among the most predictive immunotoxicity tests when included with at least two other immune parameters. The DTH assay has the advantage of being: (1) a useful measure of cell-mediated immunity, (2) an in vivo assay where there is… CONTINUE READING