The degree of redundancy in metabolic genes is linked to mode of metabolism.

@article{Mahadevan2008TheDO,
  title={The degree of redundancy in metabolic genes is linked to mode of metabolism.},
  author={Radhakrishnan Mahadevan and Derek R. Lovley},
  journal={Biophysical journal},
  year={2008},
  volume={94 4},
  pages={1216-20}
}
An understanding of the factors favoring the maintenance of duplicate genes in microbial genomes is essential for developing models of microbial evolution. A genome-scale flux-balance analysis of the metabolic network of Saccharomyces cerevisiae has suggested that gene duplications primarily provide increased enzyme dosage to enhance metabolic flux because the incidence of gene duplications in essential genes is no higher than that in nonessential genes. Here, we used genome-scale metabolic… CONTINUE READING

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