The degradation of Abeta(25-35) by the serine protease plasmin is inhibited by aluminium.

Abstract

The catabolism of amyloid beta peptides (Abeta) may be important in their accumulation in the brain in both early and late-onset Alzheimer's disease (AD). The serine protease plasmin is one of a suite of proteases implicated in AD. It is a promoter of alpha-cleavage of the amyloid beta precursor protein (AbetaPP) and will degrade Abeta in vitro. Herein we… (More)

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@article{Korchazhkina2002TheDO, title={The degradation of Abeta(25-35) by the serine protease plasmin is inhibited by aluminium.}, author={Olga V. Korchazhkina and Alison E Ashcroft and Tam{\'a}s Kiss and Christopher Exley}, journal={Journal of Alzheimer's disease : JAD}, year={2002}, volume={4 5}, pages={357-67} }