The defensin peptide of the malaria vector mosquito Anopheles gambiae: antimicrobial activities and expression in adult mosquitoes.

@article{Vizioli2001TheDP,
  title={The defensin peptide of the malaria vector mosquito Anopheles gambiae: antimicrobial activities and expression in adult mosquitoes.},
  author={Jacopo Vizioli and Adam M. Richman and Sandrine Uttenweiler-Joseph and Claudia Blass and Philippe Bulet},
  journal={Insect biochemistry and molecular biology},
  year={2001},
  volume={31 3},
  pages={241-8}
}
A recombinant Anopheles gambiae defensin peptide was used to define the antimicrobial activity spectrum against bacteria, filamentous fungi and yeast. Results showed that most of the Gram-positive bacterial species tested were sensitive to the recombinant peptide in a range of concentrations from 0.1 to 0.75 microM. No activity was detected against Gram-negative bacteria, with the exception of some E. coli strains. Growth inhibitory activity was detected against some species of filamentous… CONTINUE READING

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