The defect in delayed-type hypersensitivity of young adult SJL mice is due to a lack of functional antigen-presenting cells.

@article{Stohlman1985TheDI,
  title={The defect in delayed-type hypersensitivity of young adult SJL mice is due to a lack of functional antigen-presenting cells.},
  author={Stephen A. Stohlman and Glenn K. Matsushima and N L Casteel and Jeffrey A Frelinger},
  journal={European journal of immunology},
  year={1985},
  volume={15 9},
  pages={913-6}
}
SJL mice exhibit a strain-specific age-dependent delay in the maturation of delayed-type hypersensitivity (DTH) responsiveness. They do not attain "adult" levels of DTH responsiveness until the 10th week of age, which is 4 to 6 weeks later than the other strains of mice tested. In this report we demonstrate that spleen cells, resident peritoneal cells and thioglycollate-elicited peritoneal exudate cells are all able to transfer DTH responsiveness from naive 12-week-old DTH responders to 6-week… CONTINUE READING