The decrease of soluble RAGE levels in rheumatoid arthritis patients following hormone replacement therapy is associated with increased bone mineral density and diminished bone/cartilage turnover: a randomized controlled trial.


OBJECTIVE The aim of the study was to prospectively investigate the effects of HRT on serum soluble receptor for advanced glycation end product (sRAGE) levels in RA patients and to determine whether sRAGE production is related to bone/cartilage metabolism. METHODS Eighty-eight post-menopausal RA patients were randomized to receive vitamin D3 and calcium… (More)
DOI: 10.1093/rheumatology/kep079


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