The decellularized porcine heart valve matrix in tissue engineering: platelet adhesion and activation.

@article{Kasimir2005TheDP,
  title={The decellularized porcine heart valve matrix in tissue engineering: platelet adhesion and activation.},
  author={Marie-Theres Kasimir and Guenter Weigel and Jyotindra Sharma and Erwin Rieder and Gernot Seebacher and Ernst Wolner and Paul Simon},
  journal={Thrombosis and haemostasis},
  year={2005},
  volume={94 3},
  pages={
          562-7
        }
}
An approach in tissue engineering of heart valves is the use of decellularized xenogeneic matrices to avoid immune response after implantation. The decellularization process must preserve the structural components of the extracellular matrix to provide a biomechanically stable scaffold. However, it is known that in vascular lesions platelet adhesion to extracellular matrix components occurs and platelet activation is induced. In the present study we examined the effects of a decellularized… CONTINUE READING

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