The de novo generation of germinal centers is an oligoclonal process.

@article{Kroese1988TheDN,
  title={The de novo generation of germinal centers is an oligoclonal process.},
  author={Frans G. M. Kroese and Auk S. Wubbena and H G Seijen and Paul Nieuwenhuis},
  journal={Advances in experimental medicine and biology},
  year={1988},
  volume={237},
  pages={245-50}
}