The db/db Mouse: A Useful Model for the Study of Diabetic Retinal Neurodegeneration

@inproceedings{Bogdanov2014TheDM,
  title={The db/db Mouse: A Useful Model for the Study of Diabetic Retinal Neurodegeneration},
  author={Patricia Bogdanov and L{\'i}dia Corraliza and Josep A. Villena and Andrea Roveri de Carvalho and Jose Garcia-Arumi and David Tarazona Ramos and Jes{\'u}s Ruberte and Rafael Sim{\'o} and Cristina Hern{\'a}ndez},
  booktitle={PloS one},
  year={2014}
}
BACKGROUND To characterize the sequential events that are taking place in retinal neurodegeneration in a murine model of spontaneous type 2 diabetes (db/db mouse). METHODS C57BLKsJ-db/db mice were used as spontaneous type 2 diabetic animal model, and C57BLKsJ-db/+ mice served as the control group. To assess the chronological sequence of the abnormalities the analysis was performed at different ages (8, 16 and 24 weeks). The retinas were evaluated in terms of morphological and functional… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 39 CITATIONS

Modulation of microglia in the retina: new insights into diabetic retinopathy

  • Acta Diabetologica
  • 2017
VIEW 4 EXCERPTS
CITES BACKGROUND, RESULTS & METHODS
HIGHLY INFLUENCED

Effects of Liposomal Formulation of Citicoline in Experimental Diabetes-Induced Retinal Neurodegeneration

  • International journal of molecular sciences
  • 2018
VIEW 2 EXCERPTS
CITES METHODS & BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 68 REFERENCES

Pro-apoptotic and survival signaling in the neuroretina at early stages of diabetic retinopathy

AM Valverde, S Miranda, M Garcı́a-Ramı́rez, A González-Rodriguez, C Hernández
  • Mol Vis
  • 2013
VIEW 1 EXCERPT

European Consortium for the Early Treatment of Diabetic Retinopathy

R Simó, C Hernández
  • Br J Ophthalmol
  • 2012

Similar Papers

Loading similar papers…