The dark side of "the force" - lipid nanoparticles enhance the oncogenesis of diethylnitrosamine and result in liver cancer in mice.

@article{Zhang2017TheDS,
  title={The dark side of "the force" - lipid nanoparticles enhance the oncogenesis of diethylnitrosamine and result in liver cancer in mice.},
  author={Wei Zhang and H Gu and Xiaojun Li and Yu-Sang Li and He-Bin Tang and Gui-hua Tian and Hongcai Shang},
  journal={Nanomedicine : nanotechnology, biology, and medicine},
  year={2017},
  volume={13 2},
  pages={701-711}
}
Nano-carriers, especially lipid nanoparticles have been used widely in "a good manner", for instance in the treatment of cancer, by enhancing the targetability and reducing required dose. Here in the contrary, we presented a new possibility: nanoDEN, a nanoparticle-packed "bad guy", which is more effective and efficient in generating liver tumor in mice. We… CONTINUE READING