The dachshund gene is required for the proper guidance and branching of mushroom body axons in Drosophila melanogaster.


The dachshund gene encodes a transcription factor required for the proper development of Drosophila eyes, legs, and mushroom bodies. The mushroom bodies of dachshund mutants exhibit a marked reduction in the size of the vertical lobes and disorganization of the horizontal lobes. In mosaic animals, mutant axons fail to contribute significantly to the… (More)