The dMRP/CG6214 gene of Drosophila is evolutionarily and functionally related to the human multidrug resistance-associated protein family.

@article{Tarnay2004TheDG,
  title={The dMRP/CG6214 gene of Drosophila is evolutionarily and functionally related to the human multidrug resistance-associated protein family.},
  author={J N Tarnay and Fl{\'o}ra Szeri and Aris Ilias and Tarmo Annilo and C Sung and Olivier Le Saux and Andr{\'a}s V{\'a}radi and M. Dean and Charles D. Boyd and Steven Robinow},
  journal={Insect molecular biology},
  year={2004},
  volume={13 5},
  pages={539-48}
}
ATP-binding cassette (ABC) transporters are involved in the transport of substrates across biological membranes and are essential for many cellular processes. Of the fifty-six Drosophila ABC transporter genes only white, brown, scarlet, E23 and Atet have been studied in detail. Phylogenetic analyses identify the Drosophila gene dMRP/CG6214 as an orthologue… CONTINUE READING