The cytoplasmic protein Pacsin 2 in kidney development and injury repair.

@article{Yao2013TheCP,
  title={The cytoplasmic protein Pacsin 2 in kidney development and injury repair.},
  author={Gang Yao and Annouck Luyten and Ayumi Takakura and Markus Plomann and Jing Zhou},
  journal={Kidney international},
  year={2013},
  volume={83 3},
  pages={
          426-37
        }
}
The protein kinase C and casein kinase 2 substrate in neurons (Pacsin) is a subfamily of membrane-binding proteins that participates in vesicle trafficking and cytoskeleton organization. Here, we studied Pacsin 2 in kidney development and repair following injury. In the postnatal developing kidneys, Pacsin 2 was found to be expressed in both ureteric bud- and mesenchyme-derived structures including proximal and distal tubules, Bowman's capsule, and the glomerular tuft. In the adult kidney, its… CONTINUE READING
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