The cytochrome b5-fold: an adaptable module.

  title={The cytochrome b5-fold: an adaptable module.},
  author={Florence Lederer},
  volume={76 7},
The family of b5-like cytochromes encompasses, besides cytochrome b5 itself, hemoprotein domains covalently associated with other redox proteins, in flavocytochrome b2 (L-lactate dehydrogenase), sulfite oxidase and assimilatory nitrate reductase. A comparison of about 40 amino acid sequences deposited in data banks shows that eight residues are invariant and about 15 positions carry strongly conservative substitutions. Examination of the location of these invariant and conserved positions in… CONTINUE READING