The cytochemistry of acute leukemia: observations on glycogen and neutral fat in bone marrow aspirates.

Abstract

E XAMINATION of bone marrow aspirates using Romanowsky stains, phase preparations and tissue sections is not always sufficient to identify the malignant cell line in acute leukemia. Several histochemical technics have been explored in attempts to demonstrate characteristic cellular components of primitive cells of the various cell lines. In 1963, Wright demonstrated the absence of glycogen and the presence of neutral fat in the cytoplasm of the primitive lymphoreticular cells of African children with Burkitt’s tumor.’ His results have been confirmed in a study of a group of American children and young adults with Burkitt-like tumors.2 The purpose of this paper is to report the findings of a similar study in a series of acute leukemias, evaluated retrospectively.

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@article{Bennett1969TheCO, title={The cytochemistry of acute leukemia: observations on glycogen and neutral fat in bone marrow aspirates.}, author={J M Bennett and Tracey Dutcher}, journal={Blood}, year={1969}, volume={33 2}, pages={341-7} }