The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy

@article{Wilkinson2011TheCK,
  title={The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy},
  author={Simon Wilkinson and Daniel R. Croft and J O'prey and Arenda D. Meedendorp and Mary O'Prey and Christine Duf{\`e}s and Kevin M. Ryan},
  journal={Autophagy},
  year={2011},
  volume={7},
  pages={1295 - 1301}
}
(Macro)autophagy is a membrane-trafficking process that serves to sequester cellular constituents in organelles termed autophagosomes, which target their degradation in the lysosome. Autophagy operates at basal levels in all cells where it serves as a homeostatic mechanism to maintain cellular integrity. The levels and cargoes of autophagy can, however, change in response to a variety of stimuli, and perturbations in autophagy are known to be involved in the aetiology of various human diseases… Expand
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