The cyclic AMP receptor protein modulates colonial morphology in Vibrio cholerae.

@article{Liang2007TheCA,
  title={The cyclic AMP receptor protein modulates colonial morphology in Vibrio cholerae.},
  author={Weili Liang and A. Jorge da Silva and Jorge A Benitez},
  journal={Applied and environmental microbiology},
  year={2007},
  volume={73 22},
  pages={7482-7}
}
Inactivation of the quorum-sensing regulator HapR causes Vibrio cholerae El Tor biotype strain C7258 to adopt a rugose colonial morphology that correlates with enhanced biofilm formation. V. cholerae mutants lacking the cyclic AMP (cAMP) receptor protein (CRP) produce very little HapR, which results in elevated expression of Vibrio exopolysaccharide (vps) genes and biofilm compared to the wild type. However, Deltacrp mutants still exhibited smooth colonial morphology and expressed reduced… CONTINUE READING

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