The cutaneous innate immune response in patients with atopic dermatitis.

  title={The cutaneous innate immune response in patients with atopic dermatitis.},
  author={I-Hsin Kuo and Takeshi Yoshida and Anna de Benedetto and Lisa A. Beck},
  journal={The Journal of allergy and clinical immunology},
  volume={131 2},
Orchestrating when and how the cutaneous innate immune system should respond to commensal or pathogenic microbes is a critical function of the epithelium. The cutaneous innate immune system is a key determinant of the physical, chemical, microbial, and immunologic barrier functions of the epidermis. A malfunction in this system can lead to an inadequate host response to a pathogen or a persistent inflammatory state. Atopic dermatitis is the most common inflammatory skin disorder and… CONTINUE READING
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