The cut‐off levels of CD23 expression in the differential diagnosis of MCL and CLL

  title={The cut‐off levels of CD23 expression in the differential diagnosis of MCL and CLL},
  author={G. Barna and L. Reiniger and P{\'e}ter T{\'a}trai and L. Kopper and A. Matolcsy},
  journal={Hematological Oncology},
  • G. Barna, L. Reiniger, +2 authors A. Matolcsy
  • Published 2008
  • Medicine
  • Hematological Oncology
  • Flow cytometric analysis of CD23 expression in CD5‐positive B‐cells is a widely applied method in the differential diagnosis of chronic lymphocytic leukaemia (CLL) and mantle cell lymphoma (MCL). According to the most accepted criteria, the leukaemic cell population is CD19/CD5/CD23 triple positive in CLL but CD23‐negative in MCL. Recently, several groups have reported CD23‐positive MCL cases; however, these studies mostly analysed only CD23 positivity but not intensity. To determine the role… CONTINUE READING
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