The current therapy for mitral regurgitation.

  title={The current therapy for mitral regurgitation.},
  author={Blase Anthony Carabello},
  journal={Journal of the American College of Cardiology},
  volume={52 5},
In addressing the current therapy for mitral regurgitation (MR), it is useful to distinguish primary MR from secondary (functional) MR. In primary MR, abnormalities of one or more of the components of the mitral valve cause it to leak, imparting a volume overload on the left ventricle (LV). Severe prolonged primary MR leads to LV remodeling, myocardial dysfunction, heart failure, and death. Correction of MR, preferably by valve repair rather than replacement, is curative. Severe MR by itself is… CONTINUE READING