The current functional state of local neuronal circuits controls the magnitude of a BOLD response to incoming stimuli

@article{Angenstein2010TheCF,
  title={The current functional state of local neuronal circuits controls the magnitude of a BOLD response to incoming stimuli},
  author={Frank Angenstein and Karla Krautwald and Henning Scheich},
  journal={NeuroImage},
  year={2010},
  volume={50 4},
  pages={1364-75}
}
The purpose of this study was to determine how the history-dependent activation state of neuronal networks controls fMRI signals to incoming stimuli. Simultaneous electrophysiological and blood oxygen level-dependent (BOLD) responses were monitored during stimulation of the perforant pathway with low, high, and again low intensity but, otherwise identical pulse trains. Under three different anesthetics (alpha-chloralose, medetomidine, isoflurane) consecutive low intensity stimulation trains… CONTINUE READING