The csgD mRNA as a hub for signal integration via multiple small RNAs.

The transcription factor CsgD governing the production of curli fimbriae and cellulose is a key player in the complex regulatory circuit that decides whether Escherichia coli form biofilms. The csgD gene itself is tightly controlled at the level of transcription by a large array of DNA-binding proteins, but what happens after transcription is less… CONTINUE READING