The crystal structure of lambda-Gam protein suggests a model for RecBCD inhibition.

@article{Court2007TheCS,
  title={The crystal structure of lambda-Gam protein suggests a model for RecBCD inhibition.},
  author={Robert Court and Nicola J. Cook and Kayarat Saikrishnan and Dale B. Wigley},
  journal={Journal of molecular biology},
  year={2007},
  volume={371 1},
  pages={25-33}
}
In Escherichia coli, RecBCD processes double-stranded DNA breaks during the initial stages of homologous recombination. RecBCD contains helicase and nuclease activities, and unwinds and digests the blunt-ended DNA until a specific eight-nucleotide sequence, Chi, is encountered. Chi modulates the nuclease activity of RecBCD and results in a resected DNA end, which is a substrate for RecA during subsequent steps in recombination. RecBCD also acts as a defence mechanism against bacteriophage… CONTINUE READING

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