The crystal structure of a major allergen from plants.

  title={The crystal structure of a major allergen from plants.},
  author={Kristofer Thorn and Hans Ewald Christensen and Russell Shigeta and Donald P. Huddler and Lamaat Shalaby and Uno Lindberg and Nam Hai Chua and Clarence Schutt},
  volume={5 1},
BACKGROUND Profilins are small eukaryotic proteins involved in modulating the assembly of actin microfilaments in the cytoplasm. They are able to bind both phosphatidylinositol-4,5-bisphosphate and poly-L-proline (PLP) and thus play a critical role in signaling pathways. Plant profilins are of interest because immunological cross-reactivity between pollen and human profilin may be the cause of hay fever and broad allergies to pollens. RESULTS The determination of the Arabidopsis thaliana… CONTINUE READING