The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 Å resolution

@article{Alekshun2001TheCS,
  title={The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 {\AA} resolution},
  author={Michael N. Alekshun and Stuart B. Levy and Tanya R. Mealy and Barbara A. Seaton and James F. Head},
  journal={Nature Structural Biology},
  year={2001},
  volume={8},
  pages={710-714}
}
MarR is a regulator of multiple antibiotic resistance in Escherichia coli. It is the prototypical member of the MarR family of regulatory proteins found in bacteria and archaea that play important roles in the development of antibiotic resistance, a global health problem. Here we describe the crystal structure of the MarR protein, determined at a resolution of 2.3 Å. This is the first reported crystal structure of a member of this newly-described protein family. The structure shows MarR as a… 

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