The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy.

@article{Gaeta2005TheCR,
  title={The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy.},
  author={Alessandra Gaeta and Robert C. Hider},
  journal={British journal of pharmacology},
  year={2005},
  volume={146 8},
  pages={1041-59}
}
The variety of factors and events involved in neurodegeneration renders the subject a major challenge. Neurodegenerative disorders include a number of different pathological conditions, which share similar critical metabolic processes, such as protein aggregation and oxidative stress, both of which are associated with the involvement of metal ions. In this review, Alzheimer's disease, Parkinson's disease and prion disease are discussed, with the aim of identifying common trends underlying these… CONTINUE READING

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