The crucial role of macrophages in lymphangiogenesis.

  title={The crucial role of macrophages in lymphangiogenesis.},
  author={Dontscho Kerjaschki},
  journal={The Journal of clinical investigation},
  volume={115 9},
Lymphangiogenesis is associated with pathological processes such as the metastatic spread of carcinoma cells and organization of immunologically active lymphocytic infiltrates following organ transplantation. It has not yet been established whether expansion of the lymphatic vascular meshwork is driven by incorporation of progenitor cells or by local endothelial cell division. In this issue of the JCI, Maruyama et al. provide evidence that after mouse corneal transplant, CD11b+ macrophages… CONTINUE READING