The crowd you're in with: effects of different types of crowding agents on protein aggregation.

Abstract

The intracellular environment contains high concentrations of macromolecules occupying up to 30% of the total cellular volume. Presence of these macromolecules decreases the effective volume available for the proteins in the cell and thus increases the effective protein concentrations and stabilizes the compact protein conformations. Macromolecular crowding… (More)
DOI: 10.1016/j.bbapap.2013.11.004

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Cite this paper

@article{Breydo2014TheCY, title={The crowd you're in with: effects of different types of crowding agents on protein aggregation.}, author={Leonid Breydo and Krishna Reddy Desi Reddy and Alessandro Piai and Isabella C. Felli and Roberta Pierattelli and Vladimir N. Uversky}, journal={Biochimica et biophysica acta}, year={2014}, volume={1844 2}, pages={346-57} }