The crosslinking degree controls the mechanical, rheological, and swelling properties of hyaluronic acid microparticles.

Abstract

Viscosupplements, used for treating joint and cartilage diseases, restore the rheological properties of synovial fluid, regulate joint homeostasis and act as scaffolds for cell growth and tissue regeneration. Most viscosupplements are hydrogels composed of hyaluronic acid (HA) microparticles suspended in fluid HA. These microparticles are crosslinked with… (More)
DOI: 10.1002/jbm.a.35225

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