The critical role of hematopoietic cells in lipopolysaccharide-induced airway inflammation.

@article{Hollingsworth2005TheCR,
  title={The critical role of hematopoietic cells in lipopolysaccharide-induced airway inflammation.},
  author={John W. Hollingsworth and Benny J. Chen and David M. Brass and Katie Berman and Michael D Gunn and Donald N. Cook and David A Schwartz},
  journal={American journal of respiratory and critical care medicine},
  year={2005},
  volume={171 8},
  pages={
          806-13
        }
}
Rapid and selective recruitment of neutrophils into the airspace in response to LPS facilitates the clearance of bacterial pathogens. However, neutrophil infiltration can also participate in the development and progression of environmental airway disease. Previous data have revealed that Toll-like receptor 4 (tlr4) is required for neutrophil recruitment to the lung after either inhaled or systemically administrated LPS from Escherichia coli. Although many cell types express tlr4, endothelial… CONTINUE READING

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