The coxsackie B virus and adenovirus receptor resides in a distinct membrane microdomain.

@article{Excoffon2003TheCB,
  title={The coxsackie B virus and adenovirus receptor resides in a distinct membrane microdomain.},
  author={Katherine Julie Diane Ashbourne Excoffon and Thomas O. Moninger and Joseph Zabner},
  journal={Journal of virology},
  year={2003},
  volume={77 4},
  pages={2559-67}
}
The coxsackie B virus and adenovirus receptor (CAR) is a member of the immunoglobulin superfamily. In addition to activity as a viral receptor, it may play a role in cellular adhesion. We asked what determines the cell membrane microdomain of CAR. We found that CAR is localized to a novel lipid-rich microdomain similar to that of the low-density lipoprotein receptor (LDLR) but distinct from that of a CAR variant that exhibited traditional lipid raft localization via fusion to a… CONTINUE READING
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