The cox protein of bacteriophage P2 inhibits the formation of the repressor protein and autoregulates the early operon.

@article{Saha1987TheCP,
  title={The cox protein of bacteriophage P2 inhibits the formation of the repressor protein and autoregulates the early operon.},
  author={Sibu Saha and Elisabeth Hagg{\aa}rd-Ljungquist and Kurt Nordstr{\"o}m},
  journal={The EMBO journal},
  year={1987},
  volume={6 10},
  pages={3191-9}
}
The cox gene is the first gene of the early operon of bacteriophage P2. The early promoter Pe and the repressor promoter Pc are located close to each other and in such a way that their transcripts have opposite polarity and show an overlap of about 30 nucleotides. The expression of the early operon and of the C gene was studied in vivo by using fusions to a promoterless cat (chloramphenicol acetyl transferase) gene. The results show that the Cox protein negatively autoregulates the early operon… CONTINUE READING

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