The costimulatory function of antigen-presenting cells.

@article{Weaver1990TheCF,
  title={The costimulatory function of antigen-presenting cells.},
  author={Casey T Weaver and Emil R. Unanue},
  journal={Immunology today},
  year={1990},
  volume={11 2},
  pages={
          49-55
        }
}
  • Casey T Weaver, Emil R. Unanue
  • Published in Immunology today 1990
  • Biology, Medicine
  • In addition to the expression of MHC-antigen complexes and molecules which non-specifically promote cell adhesion, antigen-presenting cells (APCs) provide costimulatory activity for T-lymphocyte stimulation. Costimulatory molecules are essential for activation and multiplication: the presentation of antigen by cells lacking such molecules may lead to T-cell tolerance. In this review, Casey Weaver and Emil Unanue update information on interleukin 1 (IL-1), the original and best-studied… CONTINUE READING

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