The cost of natural selection
@article{Haldane2008TheCO, title={The cost of natural selection}, author={J. Haldane}, journal={Journal of Genetics}, year={2008}, volume={55}, pages={511-524} }
SummaryUnless selection is very intense, the number of deaths needed to secure the substitution, by natural selection, of one gene for another at a locus, is independent of the intensity of selection. It is often about 30 times the number of organisms in a generation. It is suggested that, in horotelic evolution, the mean time taken for each gene substitution is . about 300 generations. This accords with the observed slowness of evolution.
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References
SHOWING 1-10 OF 33 REFERENCES
The relation between density regulation and natural selection
- Biology, Medicine
- Proceedings of the Royal Society of London. Series B - Biological Sciences
- 1956
- 189
The theory of selection for melanism in Lepidoptera
- Biology
- Proceedings of the Royal Society of London. Series B - Biological Sciences
- 1956
- 60
- PDF
A résumé of investigations on the evolution of melanism in the Lepidoptera
- Biology
- Proceedings of the Royal Society of London. Series B - Biological Sciences
- 1956
- 66