The cortisol awakening response: More than a measure of HPA axis function
@article{Clow2010TheCA, title={The cortisol awakening response: More than a measure of HPA axis function}, author={Angela Clow and Frank Hucklebridge and Tobias Stalder and Phil Evans and Lisa Thorn}, journal={Neuroscience \& Biobehavioral Reviews}, year={2010}, volume={35}, pages={97-103} }
531 Citations
The cortisol awakening response--applications and implications for sleep medicine.
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Associations between the cortisol awakening response and heart rate variability
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The cortisol awakening response and major depression: examining the evidence
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The studies reveal an important, but complex, association between CAR and vulnerability to depression, and showcase longitudinal studies showing the role of CAR in predicting depression onset and recurrence.
A minimal physiologically based model of the HPA axis under influence of the sleep-wake cycles.
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A first step towards a physiologically based mathematical model of the HPA-axis under effects of the sleep-wake cycles is presented, which accounts for 3 major characteristics of daily cortisol profile in the blood.
Do infants show a cortisol awakening response?
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Both group-level and dyadic-level analyses showed that cortisol levels for mother-infant dyads were associated and cortisol levels did not significantly rise or fall following naps.
Stress, the cortisol awakening response and cognitive function.
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Brain preparedness: The proactive role of the cortisol awakening response in hippocampal-prefrontal functional interactions
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Assessing the daily stability of the cortisol awakening response in a controlled environment
- Medicine, PsychologyBMC psychology
- 2016
The stability of the CAR profile and total cortisol secretion, but not awakening cortisol levels or the magnitude of increase, was demonstrated across two consecutive mornings of measurement in a highly-controlled environment.
State variation in the cortisol awakening response
- Psychology, BiologyStress
- 2013
This is the first review to examine studies which, although limited in number, offer a relatively coherent emerging story about state factors that influence the CAR and the impact of the CAR on daily functioning and highlights areas that require greater clarification.
References
SHOWING 1-10 OF 101 REFERENCES
The cortisol awakening response (CAR): facts and future directions.
- BiologyInternational journal of psychophysiology : official journal of the International Organization of Psychophysiology
- 2009
Is the cortisol awakening rise a response to awakening?
- Biology, MedicinePsychoneuroendocrinology
- 2007
Evidence for extrapituitary mechanisms mediating the morning peak of plasma cortisol in man.
- Biology, MedicineThe Journal of clinical endocrinology and metabolism
- 1984
The finding that oscillations of plasma cortisol concentrations, comparable to the physiological morning peak, were demonstrable in ACTH-deficient patients when they were supplied with subthreshold amounts of exogenous ACTH argued against the classic concept that the adrenal cortex is invariably linked to immediately preceding episodes of pituitary ACTH secretion.
Circadian regulation of cortisol after hippocampal damage in humans
- Medicine, BiologyBiological Psychiatry
- 2004
No morning cortisol response in patients with severe global amnesia
- Biology, PsychologyPsychoneuroendocrinology
- 2005
The Awakening Cortisol Response: Methodological Issues and Significance
- Medicine, PsychologyStress
- 2004
A review explores reasons for discrepancies in normative data including confounding factors such as gender, age, awakening time, light and participant adherence that suggest the awakening cortisol response is under a distinct regulatory influence different from the rest of the diurnal cortisol secretory cycle.
Enhanced negative feedback sensitivity of the hypothalamus–pituitary–adrenal axis in chronic myogenous facial pain ⋆
- Medicine, PsychologyEuropean journal of pain
- 2009
Neural circuitry in the regulation of adrenal corticosterone rhythmicity
- Biology, MedicineEndocrine
- 2007
Adrenal cortical secretion of glucocorticoids is an essential adaptive response of an organism to stress. Although the hypothalamic-pituitary-adrenal axis regulates the adrenal cortex via release of…
Functional mineralocorticoid receptor (MR) gene variation influences the cortisol awakening response after dexamethasone
- Biology, MedicinePsychoneuroendocrinology
- 2010