The cortical innate immune response increases local neuronal excitability leading to seizures.

@article{Rodgers2009TheCI,
  title={The cortical innate immune response increases local neuronal excitability leading to seizures.},
  author={Krista M. Rodgers and Mark R Hutchinson and Alexis L Northcutt and Steven F. Maier and Linda R. Watkins and Daniel S. Barth},
  journal={Brain : a journal of neurology},
  year={2009},
  volume={132 Pt 9},
  pages={2478-86}
}
Brain glial cells, five times more prevalent than neurons, have recently received attention for their potential involvement in epileptic seizures. Microglia and astrocytes, associated with inflammatory innate immune responses, are responsible for surveillance of brain damage that frequently results in seizures. Thus, an intriguing suggestion has been put… CONTINUE READING