The correlated evolution of Runx2 tandem repeats, transcriptional activity, and facial length in Carnivora

@article{Sears2007TheCE,
  title={The correlated evolution of Runx2 tandem repeats, transcriptional activity, and facial length in Carnivora},
  author={K. Sears and A. Goswami and J. J. Flynn and L. Niswander},
  journal={Evolution & Development},
  year={2007},
  volume={9}
}
SUMMARY To assess the ability of protein‐coding mutations to contribute to subtle, inter‐specific morphologic evolution, here, we test the hypothesis that mutations within the protein‐coding region of runt‐related transcription factor 2 (Runx2) have played a role in facial evolution in 30 species from a naturally evolving group, the mammalian order Carnivora. Consistent with this hypothesis, we find significant correlations between changes in Runx2 glutamine–alanine tandem‐repeat ratio, and… Expand
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