The coronavirus is here to stay — here’s what that means
@article{Phillips2021TheCI, title={The coronavirus is here to stay — here’s what that means}, author={Nicky Phillips}, journal={Nature}, year={2021}, volume={590}, pages={382 - 384} }
A Nature survey shows many scientists expect the virus that causes COVID-19 to become endemic, but it could pose less danger over time. A Nature survey shows many scientists expect the virus that causes COVID-19 to become endemic, but it could pose less danger over time.
278 Citations
EVIDENCE BRIEF What Does it Mean for COVID-19 to be ‘Endemic’ and When Will We Get There?
- Medicine
- 2021
• Several factors support the likelihood of Coronavirus Disease 2019 (COVID-19) becoming endemic rather than eradicated, including high transmissibility of severe acute respiratory coronavirus 2…
Public policy (not the coronavirus) should shape what endemic means
- MedicineJournal of global health
- 2022
it is useful to revisit and clarify this term, as well as begin to define its possible main elements from a policy lens and in the context of COVID-19. Endemicity is not only a biological and health…
SARS-CoV-2 and COVID-19: A Narrative Review
- MedicineBritish Journal of Biomedical Science
- 2022
A narrative review examines certain components of the SARS-CoV-2 pandemic: its origins, early clinical data, global and UK-focussed epidemiology, vaccination, variants, and long COVID.
Fundamentals of genomic epidemiology, lessons learned from the coronavirus disease 2019 (COVID-19) pandemic, and new directions
- BiologyAntimicrobial Stewardship & Healthcare Epidemiology
- 2021
The molecular epidemiology literature is reviewed to understand its origins from the SARS epidemic through influenza events and the current COVID-19 pandemic, and advocate for improved genomic surveillance of SARS-CoV and understanding the pathogen diversity in potential zoonotic hosts.
The SARS-CoV-2 replication-transcription complex is a priority target for broad-spectrum pan-coronavirus drugs
- BiologybioRxiv
- 2021
This work systematically mapped druggable binding pockets on the experimental structure of fifteen SARS-CoV-2 proteins and analyzed their variation across twenty-seven α- and β-coronaviruses and across thousands of Sars-Cov-2 samples from COVID-19 patients to find the two most conserved Druggable sites.
Covid-19 pandemic ARDS lockdown will end within <2 months: Depends on cooperation of scholars of doctors and researchers
- MedicineClinical Medical Reviews and Reports
- 2021
Coronavirus may not go completely away but will be reduced in size and severity and its mortality greatly reduced: An optimistic hopeful minority report, Covid-19 pandemic war lockdown will end triumphantly before the start of May.
Reducing the Mobility of SARS-CoV-2 Variants to Safeguard Containments
- BusinessInter economics
- 2021
To prevent or delay the global spread of COVID-19 waves, virus mobility needs to be minimised through screening and testing strategies, which should also cover vaccinated people.
Coronavirus disease 2019 scenarios for a long-term strategy under fundamental uncertainty
- MedicineJournal of Clinical Epidemiology
- 2022
SARS, MERS and COVID-19-Associated Renal Pathology
- Medicine, BiologyEncyclopedia
- 2022
Despite being epitheliotropic viruses and predominantly affecting the respiratory system, these entities affect multiple systems and organs, including the kidneys, and recently, COVAN has been a suggested nomenclature change indicating renal involvement in coronavirus infections and its long-lasting consequences.
Mutations in SARS-CoV-2: Insights on structure, variants, vaccines, and biomedical interventions
- BiologyBiomedicine & Pharmacotherapy
- 2022
2 References
Immunological characteristics govern the transition of COVID-19 to endemicity
- Medicine, BiologyScience
- 2021
Analysis of immunological and epidemiological data on endemic human coronaviruses shows that infection-blocking immunity wanes rapidly but that disease-reducing immunity is long-lived, suggesting that once the endemic phase is reached and primary exposure is in childhood, SARS-CoV-2 may be no more virulent than the common cold.
Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection
- Biology, MedicineScience
- 2021
Results show that durable immunity against secondary COVID-19 disease is a possibility for most individuals, and assessing virus-specific immune memory over at least a 6-month period is likely necessary to ascertain the durability of immune memory to SARS-CoV-2.