The coronary collateral circulation: genetic and environmental determinants in experimental models and humans.

@article{Teunissen2012TheCC,
  title={The coronary collateral circulation: genetic and environmental determinants in experimental models and humans.},
  author={Paul F. A. Teunissen and Anton J. G. Horrevoets and Niels van Royen},
  journal={Journal of molecular and cellular cardiology},
  year={2012},
  volume={52 4},
  pages={897-904}
}
Obstruction of coronary arteries leads to an arteriogenic response. Pre-existent collateral networks enlarge, forming large conductance arteries with the capability to compensate for the loss of perfusion due to the occlusion. Interestingly, significant differences exist between patients regarding the capacity to develop such a collateral circulation. This heterogeneity in arteriogenic response is also found between and even within animal species and it strongly suggests that next to… CONTINUE READING