The copper regulon of the human fungal pathogen Cryptococcus neoformans H99.

@article{Ding2011TheCR,
  title={The copper regulon of the human fungal pathogen Cryptococcus neoformans H99.},
  author={Chen Ding and Jun Yin and Edgar Mauricio Medina Tovar and David A Fitzpatrick and Desmond G. Higgins and Dennis J Thiele},
  journal={Molecular microbiology},
  year={2011},
  volume={81 6},
  pages={1560-76}
}
Cryptococcus neoformans is a human fungal pathogen that is the causative agent of cryptococcosis and fatal meningitis in immuno-compromised hosts. Recent studies suggest that copper (Cu) acquisition plays an important role in C. neoformans virulence, as mutants that lack Cuf1, which activates the Ctr4 high affinity Cu importer, are hypo-virulent in mouse models. To understand the constellation of Cu-responsive genes in C. neoformans and how their expression might contribute to virulence, we… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 103 references

Similar Papers

Loading similar papers…