The conundrums of understanding genetic risks for autism spectrum disorders

@article{State2011TheCO,
  title={The conundrums of understanding genetic risks for autism spectrum disorders},
  author={Matthew W. State and Pat Levitt},
  journal={Nature Neuroscience},
  year={2011},
  volume={14},
  pages={1499-1506}
}
Recent advances in the genetics of autism spectrum disorders (ASDs) are offering new valuable insights into molecular and cellular mechanisms of pathology. At the same time, the emerging data challenge long-standing diagnostic conventions and the notion of phenotypic specificity. This review addresses the particular issues that attend gene discovery in neuropsychiatric and neurodevelopmental disorders and ASDs in particular, summarizes recent findings in human genetics broadly that are driving… CONTINUE READING
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