The controversial early history of cyclosporin.

  title={The controversial early history of cyclosporin.},
  author={K. F. Heusler and A Pletscher},
  journal={Swiss medical weekly},
  volume={131 21-22},
The biological effects of cyclosporin, namely immunosuppression and absence of cytotoxicity, were discovered-in the course of a general screening program in which many scientists at Sandoz were involved. Contrary to some statements in the literature both Dr J. Borel and Dr H. Stähelin markedly contributed to the discovery and characterisation of the biological profile of the drug. In its subsequent exploitation Borel played the leading role. The outstanding clinical importance and the… CONTINUE READING

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