The control over the new obtaining procedeum of indomethacin.

Abstract

The synthesis of the indomethacin (1H-indole-3-acetic acid, 1(4-chlorobenzoyl)-5-methoxy-2-methyl) was achieved through a new method, which reduces some stages from the previous methods. Both the structure of the finished product and the structures of the intermediaries were investigated by chromatographic methods (TLC, chromatography on column, GC-MSD) and… (More)

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