The control of firing pattern in nigral dopamine neurons: burst firing.

  title={The control of firing pattern in nigral dopamine neurons: burst firing.},
  author={Anthony A. Grace and Bejamin S Bunney},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={4 11},
In addition to firing in a single spiking mode, dopamine (DA) cells have been observed to fire in a bursting pattern with consecutive spikes in a burst displaying progressively decreasing amplitude and increasing duration. In vivo intracellular recording demonstrated the bursts to typically ride on a depolarizing wave (5 to 15 mV amplitude). Although the burst-firing frequency of DA cells showed little correlation with the base line firing rate, increases in firing rate were usually associated… CONTINUE READING
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