The control of adaptive immune responses by the innate immune system.

Abstract

The mammalian immune system comprises an adaptive and an innate component. The innate immune system employs a limited number of germ-line-encoded pattern-recognition receptors (PRRs) that recognize invariant pathogen-associated molecular patterns (PAMPs). In contrast, the adaptive immune system depends on the generation of a diverse repertoire of antigen… (More)
DOI: 10.1016/B978-0-12-387664-5.00003-0

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